Ximing Guo
Associate Professor


EDUCATION

Ph.D. 1991 University of Washington (Seattle)
M.S. 1987 University of Washington (Seattle)
B.S. 1983 Qingdao Ocean University (PRC)


RESEARCH AREAS

My research is on the genetics and reproduction of molluscs. I am interested in genetic mechanisms of molluscan development and reproduction, and their applications in the improvement of cultured molluscs. Currently, research in my lab is focused on three areas: 1) selective breeding for disease-resistance and superior growth in marine bivalves; 2) the development of triploids, tetraploids and other genetic constructs that are important for aquaculture and genetic analyses; and 3) genomic studies towards a better understanding of genome organization and the inheritance of economically important traits. I am also interested in mechanisms of genome evolution and the involvement of meiosis, sex and chromosomal changes.


PATENT

Guo, X. and S.K. Allen, Jr. Tetraploid Shellfish. US Patent No. 5,824,841, October 20, 1998; Australia Patent No. 701609, May 20, 1999.; EU Patent No. 0752814, April 25, 2001; China Patent No. 95192167.3, August 31, 2001.


SELECTED PUBLICATIONS

  • Yu, Z. and X. Guo. 2006. Identification and mapping of disease-resistance QTL in the eastern oyster, Crassostrea virginica Gmelin. Aquaculture doi:10.1016/j.aquaculture.2005.10.016

  • Yang, H. and X. Guo. 2006. Polyploid induction by heat shock-induced meiosis and mitosis inhibition in the dwarf surfclam Mulinia lateralis Say. Aquaculture 252:171-182.

  • Hedgecock, D. P.M. Gaffney, P. Goulletquer, X. Guo, K. Reece and G. Warr. 2005. A case for sequencing the Pacific oyster genome. J. Shellfish Res. 24(2):429-441.

  • Wang, Y., Z. Xu. J.C. Pierce and X. Guo. 2005. Characterization of eastern oyster (Crassostrea virginica Gmelin) chromosomes by fluorescence in situ hybridization with bacteriophage P1 clones. Marine Biotechnology 7:207-214.

  • Wang, H. X. Guo, G. Zhang and F. Zhang. 2004. Classification of jinjiang oysters Crassostrea rivularis (Gould, 1861) from China, based on morphology and phylogenetic analysis. Aquaculture 242:137-155.

  • Tanguy, A., X. Guo and S.E. Ford. 2004. Discovery of genes expressed in response to Perkinsus marinus challenge in eastern (Crassostrea virginica) and Pacific (C. gigas) oysters. Gene 338:121-131.

  • Gong, N., H. Yang, G. Zhang, B.J. Landau and X. Guo. 2004. Chromosome inheritance in autotriploid Pacific oyster Crassostrea gigas Thunberg. Heredity 93:408-415.

  • Wang, Y. and X. Guo, 2004. Chromosomal rearrangement in Pectinidae revealed by rRNA loci and implications for bivalve evolution. Biol. Bull. 207:247-256.

  • Wang, Y., Z. Xu and X. Guo. 2004. Differences in the rDNA-bearing chromosome divide the Asian-Pacific and Atlantic species of Crassostrea (Bivalvia, Mollusca). Biol. Bull. 206:46-54.

  • Yu, Z. and X. Guo. 2003. Genetic linkage map of the eastern oyster Crassostrea virginica Gmelin. Biol. Bull. 204:327–338.

  • Guo, X., S.E. Ford and F. Zhang. 1999. Molluscan aquaculture in China. J. Shellfish Res., 18(1):19-31.

  • Guo, X., D. Hedgecock, W.K. Hershberger, K. Cooper, and S.K. Allen, Jr., 1998. Genetic determinants of protandric sex in Crassostrea oyster. Evolution 52:394-402.

  • Guo, X. and S.K. Allen, Jr., 1997. Sex and meiosis in autotetraploid Pacific oyster, (Crassostrea gigas Thunberg). Genome 40:397-405.

  • Guo, X., G. DeBrosse, and S.K. Allen, Jr., 1996. All-triploid Pacific oysters (Crassostrea gigas Thunberg) produced by mating tetraploids and diploids. Aquaculture 142:149-161.

  • Guo, X., and S.K. Allen, Jr., 1994. Sex determination and polyploid gigantism in the dwarf-surf clam, Mulinia lateralis Say. Genetics 138:1199-1206.